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KMID : 0378019610040010087
New Medical Journal
1961 Volume.4 No. 1 p.87 ~ p.90
Studies on Transaminases of Salivary Glands


Abstract
1. Distribution of Glutamic-oxaloacetic and Glutamicpyruvic Transaminases in Salivary Glands Myong Ki Kim
Department of Biochemistry and Department of Dentistry,
Chonnam University, Kwangju, Korea
(Directed by Prof. Keun Bai Lee)
1. The occurrence in salivary glands of both glutamic-oxaloacetic (GOT) and glutamic-pyruvic transaminase (GPT) has been demonstrated by measuring the activities of the enzymes in the submaxillary, sublingual and parotid glands of dogs, cats and rabbits, and in the submaxillary glands of rats.
2. The activity of GOT exceeded GPT activity from 3 to 10 times in each of three kinds of salivary glands of dog, cat and rabbit except in the submaxillary glands of rat where the level of GOT was equal to that of GPT.
3. All of the three kinds of salivary glands of the animals examined contained considerable quantities o?GOT and GPT. Of three kinds of glands, submaxillary glands were most abundant in the contents of both GOT and GPT regardless of the animal species.
4. However, considerable species differences were noted to exist among cat, rabbit and dog in the levels of the transaminases in each of salivary glands. Thus, rabbits exceeded both cat and dog in submaxillary GOT and GPT contents. In the other salivary glands, i.e. sublingual and parotid, all three animals showed the same order of magnitude in GOT as well as in GPT levels. Dogs were characterized by its lowest levels of GOT and GPT in submaxillary glands and by the equal distribution pattern of GOT and GPT levels in submaxillary, sublingual and parotid glands.
5. From these experiments, it has also been discussed that salivary glands might be a chief source for the transaminase activity in saliva.
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